The use of PGx in Nursing Homes

Four Nursing Homes in Ontario. Measurements Potential drug therapy problems (DTPs) for study cohort were identified during a medication review by a pharmacist using pharmacogenetic (PGx) clinical decision support to identify medication change opportunities. The number of DTPs identified during a standard medication review was compared with the number [...]

Approaches and hurdles of implementing PGx in psychiatric clinic

Despite the many hurdles, PGx testing has great promise to optimize medication selection and dosing in psychiatry practice. While the clinical evidence‐base is growing, a collaborative multi‐stakeholderapproach can overcome hurdles discussed in this review. The development of user‐friendly systems for test ordering, guidelines for use and communication of results, [...]

Time course for benefits and risk with dual antiplatelet therapy

Question  What is the time course for benefit and risk with dual antiplatelet therapy for individuals with minor ischemic stroke or transient ischemic attack (TIA) who carry CYP2C19 loss-of-function (LOF) alleles? Findings  In this secondary analysis of the Ticagrelor or Clopidogrel With Aspirin in High-risk Patients With Acute Nondisabling Cerebrovascular Events II (CHANCE-2) [...]

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